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The ‘One Day One Genome’ initiative was recently launched by the Department of Biotechnology (DBT) and the Biotechnology Research and Innovation Council (BRIC) in India on November 9, 2024. The initiative’s objective is to showcase India’s vast and unique microbial potential, particularly focusing on the country’s diverse bacterial species.

The initiative emphasizes the critical roles that microbial species play in various sectors, including environment, agriculture, and human health. It seeks to promote understanding and recognition of these microorganisms in the wider community.Genome sequencing will be leveraged to explore and document the hidden microbial potential across India. This includes identifying enzymes, antimicrobial resistance traits, and bioactive compounds. Such advancements are expected to contribute to better environmental protection, agricultural improvements, and health outcomes.

The initiative aims to release fully annotated genomes of microbial species isolated from India. This data will be made available to the public, accompanied by graphical summaries and infographics to enhance understanding of both scientific and industrial applications. They contribute to biogeochemical cycles, soil formation, and the degradation of pollutants. They also facilitate processes like nitrogen fixation, nutrient cycling, and pest control in agriculture.Human Health: Microbes outnumber human cells in the body and are vital for digestion, immune function, and even mental health. Non-pathogenic microbes are crucial for defending against infections.

The ‘One Day One Genome’ initiative represents a significant step towards harnessing India’s microbial diversity for various beneficial applications. By focusing on genome sequencing and public engagement, it aims to stimulate discussions and innovations that could help enhance environmental management, agricultural productivity, and human health outcome measures.

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